Right Handed:
Place curve of the ukulele on your right thigh, and the neck into you left hand, allowing your right hand to strum the strings in front of the sound hole. Your left hand fingers will move across the frets to change the chords.
Place the curve of the body onto you leg, letting the neck fall into your right hand. Your left hand will be able to strum in front of the sound hole while your right hand moves across the frets to play chourds.